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Why you should eat: Prioritizing sources of lean protein is critical while taking semaglutide, Pincus says

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Sargeant JA, et al

Filingeri noted that this research study was designed to further examine changes in weight, body fat mass, and muscle mass in patients taking incretin medications. We found that, under close supervision and regular follow-up from an obesity medicine specialist, patients were able to lose fat mass with only a minimal decline in muscle mass. Alexandra Filingeri, DCN, RCN Filingeri pointed out that the results of this study cannot be generalized to patients receiving medication via telemedicine without routine body composition analysis, nor can they be generalized to in-person visits without utilizing body composition analysis

These developments favor therapeutic modalities, such as peptides, that can be mechanistically linked to disease pathways and monitored through pharmacodynamic readouts