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potential mechanisms

A flexible segment in DPP-4 connects the transmembrane domain to the extracellular domain and is the target of shedding, a process in which the enzyme is cleaved and released into circulation [22]

All findings to date derive from preclinical and early investigational data

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24 The anti-inflammatory effects of GLP-1RAs are better understood when these molecular details are uncovered, which may lead to novel therapeutic options for inflammatory diseases

doi: 10.1016/S2213-8587(21)00203-5 [DOI] [PubMed] [Google Scholar] 2.Epic Cosmos