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doi: 10.3389/fnut.2022.855223 Received 14 January 2022 Accepted 14 March 2022 Published 07 April 2022 Volume 9 - 2022 Edited by Christina Boyle, University of Zurich, Switzerland Reviewed by Micaela Morettini, Marche Polytechnic University, Italy

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Thirty-five trials with 13 treatments lasting a minimum of 8 weeks were included, and GLP-1R agonists were associated with modest improvements in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels, whereas there was no change in high-density lipoprotein cholesterol

10.1016/j.brainresrev.2007.05.013 155 YaribeygiH.Rashidy-PourA.AtkinS

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They then calculated an incremental cost effectiveness ratio for semaglutide (costing $700 per month per person) of $443,000 per quality-adjusted life year gained