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Concurrently, neuromodulators like dopamine, serotonin, and norepinephrine fine-tune taste sensitivity at both peripheral (taste buds) and central (reward circuitry) levels, linking chemosensation to motivational states
I long recognized that people would come to me saying, "I ran all the labs and everything looks fine." And I'd look at the same labs and see early insulin resistance

That pattern can point toward gastroparesis (severely stalled stomach emptying) or a dose thats simply too aggressive for you both of which are reasons to call your prescriber rather than ride it out
However, concerns about their potential link to cancers, such as thyroid cancer, have surfaced

doi: 10.1016/j.yfrne.2016.07.002 83 AkimotoHNegishiAOshimaSWakiyamaHOkitaMHoriiNet al

Multiple Imputation for Nonresponse in Surveys (John Wiley & Sons, 1987)
