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BMI of 28 kg/m or 24 kg/m with at least one weight-related comorbidity (such as hypertension, hyperglycaemia, sleep apnoea syndrome, dyslipidaemia and cardiovascular disease)

They should be disposed of safely in an FDA-cleared sharps disposal container

What makes the difference is the support

It affects vascular biology, inflammation, energy metabolism, body composition, and possibly brain aging

By reducing excess weight, patients experience improvements in cardiovascular health, joint function, and overall well-being, allowing them to lead more active and fulfilling lives

The incorporation of amyloid-related therapy either as an add-on or as a link to specific aspects of AD pathophysiology might become an important trend in clinical trials of new drugs in the future