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My first unanticipated serendipitous event occurred in 1967 when, because of the outbreak of the Vietnam war, I was drafted into the US Public Health Service and assigned to the NIH to undertake two years of laboratory research on the mechanisms of DNA replication

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doi: 10.1016/j.bbi.2009.05.058 62 GaultV

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Taken together, these pooled safety analyses (119123) and CV outcome safety trials (124127), together with review of published data from numerous clinical trials (39), provide reassuring evidence that the catalytic activity of the DPP-4 molecule can be modulated to enhance the beneficial metabolic effects of its substrates (such as the incretin hormones) without adversely affecting any of the protease-independent metabolic effects discussed above, or interfering with any of its other (non-metabolic) functions