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Comprehensive Phase 3 safety and efficacy data are required before a licensing decision can be considered

Homogenized lysate will be transferred to a Direct-zol RNA MiniPrep Plus spin column (Zymo Research, Irvine, USA), and RNA will be isolated by following the Direct-zol RNA Miniprep Plus manufacturers instructions

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Generally people should be started on the lower dose and increased after 3 to 6 months

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