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Key Takeaways In the first head-to-head trial (SURMOUNT-5, NEJM 2025), tirzepatide produced 20.2% average weight loss vs

Generally, injectable delivery offers higher and more consistent bioavailability, but oral options are improving rapidly and may be suitable for patients with needle anxiety

That means nearly one in three products was not even the right molecule

Do body aches get worse at higher tirzepatide doses

While the risk of medullary thyroid carcinoma in humans taking tirzepatide remains theoretical, these symptoms require urgent evaluation

About this article Cite this article Neves, J.S., Leite, A.R., Vale, C