semaglutide effect on muscle impacts skeletal to a similar extent as caloric restriction in mice with diet‐induced obesity - Jeromson - The Journal of Physiology Accidentally injected semaglutide into muscle:

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Gary Clayman, MD, explained that while animal studies have suggested a link between GLP-1 therapies and C-cell issues leading to medullary thyroid cancer, these findings have not been replicated in human studies