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442 Preclinical studies have documented the inhibitory effects of GLP-1RAs on the development of AS in animal models

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Given that the designs of GLP-1RA studies vary concerning dose, duration, and assessment modality (e.g., histology vs

Though not recommended explicitly for acute bipolar depression, these agents are often initiated alongside first-line agents as they have a good safety and efficacy record for depressive prophylaxis
Endothelial cells in blood vessels contain GLP-1 receptors

That is a large subcutaneous injection
