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Description
The evidence is strongest for semaglutide and tirzepatide

A dedicated Phase 3 trial evaluating retatrutide specifically for metabolic dysfunction-associated steatotic liver disease is currently underway

dose reductions of these agents may be required when initiating tirzepatide

Vaswani A, Shazeer N, Parmar N, et al

resistance training and adequate protein remain sensible adjuncts

Burkett WC, Clontz AD, Keku TO, Bae-Jump V (2023) The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches
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