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Image: Clickup Aspen chief executive Stephen Saad said tirzepatide is one of the therapeutic options available to physicians and said it represents an added therapeutic option to address the rising tide of NCDs in South Africa

When Orsema is added to existing therapy of sulfonylurea or insulin, a reduction in the dose of sulfonylurea or insulin should be considered to reduce the risk of hypoglycemia

Real-world outcomes are likely 10% to 20% lower than trial outcomes

However, many children fail to achieve sufficient or sustained weight loss through lifestyle changes alone, highlighting the need for adjunctive therapies

Those who continued taking semaglutide lost an additional 7.9% body weight, resulting in a total weight loss of 17.4% over the entire trial

Most people carry about 90% of their body fat as subcutaneous fat just beneath the skin, while the remaining 10% exists as visceral fat that creates serious health risks