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While clinical innovation remains important, investors must evaluate not just scientific differentiation, but also commercial execution, payer alignment, and scalability

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Clinical trials showed significant weight loss, though cardiovascular effects require careful monitoring

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Althage MC, Ford EL, Wang S, Tso P, Polonsky KS, Wice BM (2008) Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high-fat diet

visceral fat reduction up to 27%