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An increasing concentration of unlabeled GLP-2(133) or teduglutide (ranging from 0.1 nM to 1 M) followed by a fixed concentration of [ 125 I]GLP-2(133, M10Y) (1015 pM) was added to the cells and incubated for 4 h at 4 C

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In Figure 4AC, we plot how the percentage of obese US adults could decrease if a fixed annual supply of semaglutide was administered in 2.4 mg doses to either (1) a proportion of obese US adults at q1wk dosing (termed scenario (1)) or (2) twice as many obese US adults at q2wk dosing (termed scenario (2))

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