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Retatrutide, a GIP, GLP-1, and glucagon receptor agonist, for obesity: the SURMOUNT-5 trial

Future anti-obesity agents for use in older adults Several novel AOMs are currently in development, or undergoing clinical trials, that will likely be available for the treatment of obesity soon, and have included older adult participants (Table 1)

Research into oral triple agonists remains at an early stage

[DOI] [PubMed] [Google Scholar] 11.Kosteli A., Sugaru E., Haemmerle G., Martin J.F., Lei J., Zechner R., Ferrante A.W., Jr

Glucagon-like peptide 1 receptor agonist ameliorates the insulin resistance function of islet cells via the activation of PDX-1/JAK signaling transduction in C57/BL6 mice with high-fat diet-induced diabetes

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