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Parallel randomized studies in Hashimoto thyroiditis and Graves disease should pre-specify metabolic co-endpoints (Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and Magnetic Resonance Imaging-Proton Density Fat Fraction (MRI-PDFF) for liver fat) to test the immunometabolic hypothesis suggested by observational signals and secondary analyses [32,60]

Most people notice changes in food preferences and portion control within 24 weeks of starting therapy

Cell Metab (2018) 27(2):299313

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