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At present, tirzepatide is the leading GLP-1/GIP dual agonist and has been approved for marketing in many countries, including the US, Europe and Japan, for the treatment of T2D

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The underlying mechanism was revealed to be greater insulin secretion with oral vs i.v

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The clinical trial evidence on duration The landmark STEP trials for semaglutide and SURMOUNT trials for tirzepatide provide the clearest data on what happens at different treatment durations