Mechanisms of action of GLP-1RA
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Description
The half-lives of CJC 1295 and Ipamorelin are approximately 68 days and 2 hours, respectively
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This was corroborated by a marked effect on cAMP signaling in -arrestin-less HEK293 cells, which progressively diverged with longer exendin-4 treatment, reminiscent of the effect of exendin-phe1 on beta cell cAMP production
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