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Patients should be advised to: Aim for 6-8 glasses of fluid daily (approximately 1.52 litres), as recommended by the NHS, unless on a fluid restriction Note: patients with heart failure, chronic kidney disease, or other conditions requiring fluid restriction should follow their clinician's specific guidance Increase fluid consumption during episodes of nausea, vomiting, or diarrhoea Monitor urine colour as a simple indicator of hydration status (pale yellow suggests adequate hydration) Ensuring adequate electrolyte intake through dietary sources is essential

So always consult with your healthcare team before changing your medications or lifestyle

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Van der Vreken A., Meeus F., Tu C., van den Broecke L., Raimondi V., Vescovini R., Hanssens H., Watt F., Autaers D., Aragon M.M., et al

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Accessed March 4, 2025

The STEP trials demonstrated average weight loss of 14.9% of body weight at 68 weeks with the 2.4mg weekly dose