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Dual and multi-agonists, including agents targeting GLP-1/GIP and GLP-1/GCGR pathways, are emerging as next-generation therapies with enhanced metabolic benefits
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After 24 weeks of therapy weight loss was 1.7 kg and 2.56 kg among patients with mild and moderate/severe SDB, respectively
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However, Ozempic may be more likely to cause adverse effects
Similar to the alcohol-related responses, GLP-1R within the NTS, LDTg, VTA, and NAc modulates the behavioral responses induced by cocaine
