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Understanding this distinction is the single most important step you can take toward choosing a path that aligns with your body, your lifestyle, and your long-term health goals

Sitagliptin and vildagliptin are not licensed for use in renal impairment, whereas saxagliptin can be used at a reduced dose and linagliptin can be used at the only strength available

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Manufacturers are addressing these concerns, for example, by producing new formulations with fewer side effects
