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how long before you feel semaglutide What to Expect During the First Week After Your First GLP-1 Medications Explained: Dosage Chart,
Description
Most side effects, like nausea or fatigue, fade within one to two weeks

J Neurosurg, 44:337-341

Lucan, MD, MPH, MS Post "Semaglutide and tirzepatide prescriptions
For Ozempic, eructation is not listed among adverse reactions occurring in 5% of patients in clinical trials, suggesting a lower incidence at the diabetes treatment doses

Trial participants with diabetes achieved 19.7% weight loss plus 2.02% A1C reduction on average

Overall, individual responses to the medication vary, which accounts for some of the differences seen across available studies
