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An estimated 23.1% of those who took the highest dose experienced vomiting, while 36.4% and 27.4% had nausea and diarrhea, respectively
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As discussed earlier, getting rid of GLP-1 nausea often boils down to: changing your eating habits, using anti-nausea remedies like over-the-counter medications or peppermint tea, hydrating between (not during) meals, and staying upright after eating

PMID: 2890903

For those who find themselves not losing weight in the early weeks on semaglutide , patience and dose optimization are usually the answer
However, many new patients express reservations about one specific aspect: self-injections
