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Liraglutide treatment enhanced the activity of group 3 innate lymphoid cells (ILC3s), leading to elevated levels of interleukin-22 (IL-22), a key cytokine essential for epithelial regeneration (86)

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However, patients with gastroparesis often have erratic blood sugars due to delayed gastric emptying

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Studies with a pragmatic design, high discontinuation rates, or shorter study durations could have limited overall exposure to the study GLP-1 RA, which ultimately could have dampened the ability to detect a difference if one existed