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GLP-1s and Addiction The authors of GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer , appearing in October 2025 in JES, point out that the World Health Organization reported 890 million adults and 60 million children and adolescents had obesity in 2022 globally

But theres no research showing what happens when berberine is applied in patch form, he adds

Because those things determine whether or not you're going to have those complications." Part of the issue, Allen said, is that GLP-1s are relatively easy to access and often much cheaper through online pharmacies or websites, but those providers may not educate patients about their dosage or side effects

The answer lies in focusing on whole, minimally processed ingredients

Follow-up measurements taken during the 90 days on either side of these post-index dates were valid, with the closest measurement to 180/365 days post-index used as the follow-up value if multiple measurements were available