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This review highlights key clinical considerations across reproductive stages, emphasizes the primacy of human exposure data where available, and identifies critical evidence gaps requiring future prospective study

The IgG4 Fc region was selected and its sequence modified at several positions to further reduce its interaction with the Fc-y receptors to avoid ADCC immunologic side effects [86]

D., Finan, B., & Galea, L

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Major metabolites include berberrubine (A1), thalifendine (A2), demethyleneberberine (A3), and jatrorrhizine (A4), along with their glucuronide conjugates (Fig

In addition, ENS maturation and function may be regulated by the production of 5-HT by the gut microbiota 249