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First, the GIP component may explain why tirzepatide produces comparable or even lower rates of nausea despite stronger weight loss

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Pancreatitis A 2023 systematic review across five databases analyzed rates of adverse events associated with tirzepatide

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Common side effects may include: Nausea Vomiting Diarrhea Constipation Reduced appetite Abdominal discomfort Fatigue Dizziness Possible blood sugar changes Patients should seek medical guidance if side effects become severe, persistent, or difficult to manage