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Semaglutide works systemically through multiple mechanisms: it enhances insulin secretion in response to elevated blood glucose, suppresses glucagon release, slows gastric emptying, and acts on appetite centres in the brain to increase satiety and reduce hunger

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Effects of laparoscopic sleeve gastrectomy on attentional processing of food-related information: Evidence from eye-tracking

this mechanism of action has potential implications when considering pre-procedure fasting times and the choice of anesthesia technique

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Secondly, the rebound effect after stopping Ozempic can be worse if long-term weight loss cannot be maintained. With the rebound effect, women could end up at a higher weight than before