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Some patients had hypersensitivity reactions, including rash and mild swelling, but anaphylaxis was uncommon

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FDA Approval Timeline As of mid-2025, Retatrutide is: Still under investigation in phase 3 clinical trials Expected to complete primary trials by late 2025 Anticipated to receive FDA approval in 2026 Until then, it is available only for research purposes , and should not be used outside of controlled clinical settings without professional supervision