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So what does this mean for real people

PMID: 35101924

A MMRM was used for the longitudinal endpoints including covariates: treatment arm, background therapy at baseline, age, sex, dopamine transporter-single-photon emission computed tomography (DaT-SPECT), contralateral putamen binding ratio at baseline, the visit (as a categorical factor), a group-by-visit interaction and the baseline endpoint

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The only shelf life that should be followed is the one stated on the IMP label or clinical trial protocol provided by the trial sponsor

Sedimentation velocity parameters were obtained directly from the Sedfit program 52,53 using a continuous c ( s ) distribution model