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Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus

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Given that potentially dangerous islet cell hyperplasia is reported to occur in some T2DM patients treated with GLP-1R agonists, 79 it might be possible to design allosteric modulators of the GLP-1R that preferentially stimulate insulin secretion rather than islet growth

Ross, Guillermo E

Newer dual and triple agonists like retatrutide are also entering the research landscape

Using trazodone hydrochloride tablets with certain other medicines can affect each other causing serious side effects