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Semaglutide and Tirzepatide work best when combined with a balanced diet and regular exercise

patients with MASLD frequently have normal A1C yet significant hepatic disease

For the full potential of disease modification to be achieved, its a given that we must demonstrate safe, long term body composition improvement when the new medications are deployed, especially in the older population

It functions as a redox agent, meaning it can both donate and receive electrons, supporting efficient energy production in mitochondria the powerhouses of cells

Of course, there is a theoretical performance advantage in sports that have weight classes or sports like cycling and long distance running where weight is a factor, but because the GLP-1s suppress appetite and cause muscle loss as well as fat loss, they arent necessarily going to improve performance. However, Eichner also points out that not much is known about potential performance-enhancing effects of GLP-1s, and more research needs to be done

It is uncertain which mode of delivery improves the risk-benefit ratio for the patient and fetus