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Bibcode:2020PNAS..11729959K

Keywords GLP-1 Agonists SGLT-2 Inhibitors Diabetes Mellitus Chronic Kidney Disease Liver Transplantation Introduction Despite the life-saving intervention of liver transplantation for patients with ESLD (end-stage liver disease), the success of transplantation is compromised often by post-transplant complications, particularly diabetes mellitus and chronic kidney disease (CKD)

By modulating electrostatic interactions between charged peptide drugs and the polymer matrix, these hydrogels enable sustained and steady drug elution over extended periods, ranging from days to weeks, significantly reducing dosing frequency from daily to weekly or even monthly intervals [46]

This marks an increase of nearly 500 filings in a single month

10.1016/j.kint.2023.10.018 [DOI] [PubMed] [Google Scholar] 71
