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The dual mechanism may contribute to these enhanced metabolic effects through improved fat oxidation and energy expenditure

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The timing and severity of menstrual changes depend on how quickly you lose weight and your baseline metabolic state

Clarifying these relationships may help refine risk stratification, guide endocrine evaluation in selected patients, and inform integrated approaches aimed at optimizing weight loss while preserving skeletal muscle mass

This has important clinical relevance since obese and diabetic populations have been reported to have higher prevalences of NENs, implicating that such a treatment may be even more accessible and appropriate for these unique cohorts [35,36,37,38]

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