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Further trials are needed to investigate whether GLP-1 agonists, and particularly with more effective weekly agents (i.e

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Further pharmacovigilance and mechanistic studies are warranted to clarify this potential association.

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Emerging evidence suggests such neural mechanisms interact with metabolic processes to coordinate energy expenditure with energy resources, thereby linking motivation with metabolic health

Here the authors show the efficacy of GLP1-based multi-agonists, and superiority of GLP1/E, for managing metabolic complications of PCOS in preclinical models, with improvement also of some reproductive traits.