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once-daily semaglutide 30 nmol/kg at 16:00 h, for 12 weeks
Association of glucagon-like peptide-1 receptor agonists use with fracture risk in type 2 diabetes: a meta-analysis of randomized controlled trials
Derr, R
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Several of the PGDPs have important and well-defined (pharmacological) effects on systemic metabolism, including the modulation of food intake and satiety (GLP-1, glucagon, oxyntomodulin), regulation of fluid homeostasis (water intake and urine excretion) (GLP-1) [92], thermogenesis (glucagon), lipid metabolism (GLP-1, glucagon, GLP-2), gastrointestinal motility (glucagon, GLP-1, GLP-2), and gastric emptying (glucagon, GLP-1, GLP-2)
The actions of GLP-2 to stimulate small bowel growth were rapid, detectable within days, and associated with increased crypt cell proliferation (58)
