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in each case, this effect was most pronounced in the groups with T2D plus ASCVD, and unadjusted HRs were similar to adjusted HRs (online Supplementary Table S3)

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In this study, significant differences were observed across dosage groups, including a higher proportion of male participants in the 14 mg group and a greater number of participants switched from DPP-4 inhibitors in the 7 mg group ( Supplementary Figure 1 )

The TGAs medicine information describes tirzepatide as acting on both GIP and GLP-1 receptors, reducing food intake, regulating appetite, delaying gastric emptying and improving glycaemic control