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Options may include SGLT2 inhibitors, metformin, thiazolidinediones, or insulin for diabetes, noting that DPP-4 inhibitors also carry pancreatitis warnings

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Tirzepatide displayed an unprecedented glucose and body weight lowering potential, presenting also with the ability to increase insulin sensitivity, reduce systolic blood pressure and inflammation and ameliorate dyslipidemia, particularly by reducing triglycerides levels