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One study cited by Dr

They can provide guidance on diet and exercise to help manage your weight effectively while controlling your diabetes

Surprisingly discontinuation rates are also high in diabetics, a study suggests upto 47% diabetics are going off these drugs in just 1 year

Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from enteroendocrine L-cells in the gastrointestinal tract in response to nutrient intake

They draw water into the bowel, softening stools and increasing frequency Bulk-forming laxatives (ispaghula husk, methylcellulose) work similarly to dietary fibre and are generally suitable for long-term use, but should be avoided if you have severe bloating or suspected impaction Stimulant laxatives (senna, bisacodyl) should be reserved for short-term use when other measures fail Rectal treatments (glycerol suppositories, small-volume enemas) can provide rapid relief for occasional constipation Establishing a regular toilet routine can be beneficial

Efforts have focused on GLP1RAs as a therapeutic option for T2DM since they inhibit appetite and food intake and improve glucose regulation