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Sfteland E, Meier JJ, Vangen B, et al

Around 1 in 10 people carry variants in the PAM gene that can interfere with the activation of hormones, including GLP-1

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However, the efficacy of these drugs heavily relies on stringent temperature controls throughout their journey from the manufacturer to the patient

STEP Trials : These trials focused on the weight management aspect of GLP-1 therapy