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These participants were given either a reduced-calorie diet and increased physical activity alone, or these lifestyle changes plus Wegovy

Clin Res Cardiol (2025)

Hypothalamic Appetite Regulation: Investigating the activation of GLP-1 receptors in the arcuate nucleus to study reductions in caloric intake and body mass

Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbll T., SUSTAIN-6 Investigators

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3 Years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial