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4-8 Weeks and Beyond: As semaglutide GLP-1 continues to work within the system, the most substantial appetite reduction typically occurs between 4 to 8 weeks of use

Choosing the Right Option for Your Body The question isn't "which medication is better"it's "which is better for you right now." Factors That Matter Your metabolic state matters more than your weight

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Always consult your doctor about GLP-1 medications

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However, tapering over 4-8 weeks is typically easier psychologically because it prevents a sudden hunger surge and gives your brain time to solidify new eating behaviors