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These were generally mild and not classified as serious adverse events, but they establish that retatrutide does have a measurable effect on cardiac rhythm beyond simple rate increase
Biochem 214 , 829835 (1993)
It synthesises data from major clinical trials, peer-reviewed nutrition research and UK and US clinical guidelines
Subsequent cohorts were dosed after the dosing regimen in the preceding cohort was recommended to be safe and well tolerated based on the safety and laboratory data through at least day 15
And since reduced food intake on tirzepatide can lower dietary magnesium intake, supplementation addresses a potential deficiency at the same time
