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Other compounds such as bile salts and xenobiotics (399), are known to be metabolized and excreted by the microbiota, affecting the host physiology

1 Introduction 1.1 Atherosclerosis and coronary artery disease Coronary artery disease (CAD) is a cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive ( Inflammation plays a key role in the formation of atherosclerotic plaquesthe primary pathological mechanism underlying CAD ( (IFN- ) and tumour necrosis factor (TNF)- , produced by immune cells, endothelial cells, platelets and fibroblasts are associated with atherosclerosis onset and progression

Baseline assessment of reflux symptoms and consideration of concurrent acid-suppressive therapy may be appropriate in high-risk individuals

While well-tolerated, they require careful consideration of potential adverse effects and contraindications (6)

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Mounjaro and Ozempic work similarly to mimic the effects of certain hormones called incretins