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Table 12: Results at Week 24 (LOCF*) in an Active-Controlled Trial of Dapagliflozin Initial Combination Therapy with Metformin HCl Extended-Release in Adults with Type 2 Diabetes Mellitus Dapagliflozin Add-On To Metformin HCl Immediate-Release A total of 546 adult patients with type 2 diabetes mellitus with inadequate glycemic control (HbA1c 7% and 10%) participated in a 24-week, placebo-controlled trial to evaluate dapagliflozin in combination with metformin HCl (NCT00528879)

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The initiative would need to be introduced and embraced by a majority of city council in order to move forward

Under physiological conditions, Cdc42 toggles between its inactive GDP-bound form and its active GTP-bound form, regulating signaling pathways involved in cellular functions such as cell morphology, cell cycle control, actin cytoskeleton dynamics, vesicle trafficking, and cell polarity