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Unlike semaglutide, which activates only the GLP-1 receptor, or tirzepatide, which targets both GLP-1 and GIP, retatrutide engages three key metabolic receptors simultaneously: GLP-1 receptor curbs appetite, slows gastric emptying, and lowers blood sugar

After Discontinuation : They have shown promise in potentially substituting some of the medications effects

Medicare currently limits its coverage of GLP-1s to individuals with Type 2 diabetes or certain heart conditions, excluding prescriptions aimed solely at obesity

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Bierhaus, A
