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It is associated with insulin resistance as seen in type 2 diabetes mellitus

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[7] [8] This observation led to the identification of GLP-1 as one of the key incretin hormones responsible for this enhanced insulin response

They use a medication called semaglutide, part of a family of drugs called GLP-1 agonists, which work by mimicking a hormone that the body naturally makes to slow the passage of food through the stomach, which helps people feel fuller longer

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PubMed 25.Dungan K