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Histologically, perforating dermatoses are characterized by a lymphocytic infiltrate, an absence or degeneration of dermal connective tissue components (e.g., collagen, elastic fibers), and transepidermal extrusion of keratotic material

Sci Rep 14 , 24433 (2024)
Potential risks of bias were evaluated for all included trials, using a tool developed for this purpose (Rob 2) (21)

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Semaglutide is the most widely studied example

PMCID: PMC11431103
