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Capasso A, Lang J, Pitts TM, Lieu CH, Kopetz S , Davis SL, Jordan K, Bagby SM, Messersmith WA, Pelanda R, Eckhardt SG

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10.1016/s0140-6736(14)60976-4

However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program

Our findings provide clues for potential drug development targeting the autophagic pathway for the treatment of COVID-19