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Furin-mediated priming of viral S protein at S1/S2 (P R RA R 685 ) [the underlined AAs refer to critical residues needed for the furin recognition] is a key determinant in the pathogenesis of COVID-19 55,73,329

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sensitive to decreasing Se levels, and it is transcriptionally regulated by peroxisome proliferator-activated receptor (PPAR) [19]

doi: 10.1038/sj.bjc.6604422 73 JonesSEJomaryC

Normal mice in this experiment usually showed less violent movements and were more likely to interact with the newcomer, the intruder 54,55